The Innovation | Virtual Collection—Life Sciences (v2) 生命科学专辑2.0

Figure 1 Summary of Publishing (2020—2022)

图1 出版概览(2020—2022年)

Introduction: The Innovation has published 300 articles from 2020 to 2022 (Figure 1).  The authors come from 49 countries and articles belong to 9 categories (Figure 2), which have been cited by researchers from 113 countries (Source: Web of Science). The Innovation is a multidisciplinary journal covering all natural science fields. To facilitate readers to refer to articles in a specific field, Editorial Team integrates the contents from different Issues to make this Virtual Collection. 

引言：从2020到2022，The Innovation出版三卷十三期共300篇文章（图1），作者来自49个国家。这些文章分布在9个栏目（图2），已被113个国家作者引用（数据源: Web of Science）。The Innovation是综合性英文期刊，发文内容涵盖所有自然科学领域。为方便读者查看出版的某领域文章，编辑部整合这两年不同刊次的相关内容，陆续推送Virtual Collection（虚拟专辑）……在本刊发表的文章，同时在微信公众号上进行“科普化解读”——尽可能让更多人懂得文章的主旨和亮点：传播科学知识，传承科学素养；和您一起理解科技创新的最新进展与突破！2020年-2021年，出版周期为季刊；2022年-2023年，出版周期为双月刊（出版月份：1/3/5/7/9/11）

Figure 2 Categories of Publishing (2020—2022)

图2 文章全貌(2020—2022年)

About Life Sciences (v2)

生命科学 2.0

Life sciences: It aims to analyze the mysteries of life and understand the mechanisms behind various life activities, as well as the interactions amid species, natural environment and ecosystem. A huge number of biodata were produced and a lot of them are applied to upgrade medical, agricultural, breeding, electronics, materials, artificial intelligence, information and other technologies to treat diseases, improve human body functions, and provide a suitable living environment.

生命科学：生命科学旨在解析生命的奥秘，让人类理解各类生命活动背后的机制，以及生命体间、生命体与自然间的相互作用。研究者不断优化理论体系和技术手段，从原有的整体-系统-器官-组织-细胞水平，深入到目前的DNA、蛋白质、代谢物等水平刻画生命活动。海量生命科学数据助力于不断升级的医疗、农业、养殖、电子、材料、人工智能、信息等领域的发展；为开展疾病治疗、改善生命机能，可持续的生存环境提供了保障。本次虚拟专辑收录与生命科学相关的Translational Patent 1篇，Editorial 4篇，News & Buzz 7篇，Perspective 7篇, Article 8篇，Report 23篇，Commentary 35篇，Review 7篇，Out-of-the-Box 1篇；共计93篇。

Section 1

Translational Patent

Hyper-seq: A novel, effective and flexible marker-assisted selection and genotyping approach

Section 2

Editorials

Understanding the plant diversity on the roof of the world

Different virus, same mistakes: Why (re-) emerging viruses are one step ahead of us

To manage long COVID by selective SARS-CoV-2 infection biosensing.

Bioassay development for public health emergency

Section 3

News & Buzz

Protist 10,000 genomes project

Dealing with highly pathogenic avian influenza: An impending crisis

Towards post-2020 global biodiversity conservation: Footprint and direction in China

Stem cell research finds possible HIV cure with cord blood transplant

Zoonotic attack: An underestimated threat of SARS-CoV-2?

Omicron XE emerges as SARS-CoV-2 keeps evolving

The first Chinese oral anti-COVID-19 drug Azvudine launched

Section 4

Perspectives

Comprehensive knowledge of reservoir hosts is key to mitigate future pandemics

Integration of soft electronics and biotissues

From unusual suspect to serial killer: Cyanotoxins boosted by climate change may jeopardize megafauna

Exposome in human health: Utopia or wonderland?

China’s low emission pathways toward climate-neutral livestock production for animal-derived foods

Searching for unity in diversity of animal magnetoreception: from biology to quantum mechanics and back

The continuous evolution of 2D cell-traction forces quantification technology

 Section 5

Articles

Impact of immunization programs on 11 childhood vaccine-preventable diseases in China: 1950-2018

Massive cranium from Harbin in northeastern China establishes a new Middle Pleistocene human lineage

clusterProfiler 4.0: A universal enrichment tool for interpreting omics data

Host-specific asymmetric accumulation of mutation types reveals that the origin of SARS-CoV-2 is consistent with a natural process

Synergistic engineering of CRISPR-Cas nucleases enables robust mammalian genome editing

Temperature acclimation in hot-spring snakes and the convergence of cold response

A neutralizing-protective supersite of human monoclonal antibodies for yellow fever virus

Direct evidence of CRISPR/Cas9-mediated mitochondrial genome editing

 Section 6

Reports

Regulatory role of retinoic acid in male pregnancy of the seahorse

A static magnetic field improves iron metabolism and prevents high-fat-diet/streptozocin-induced diabetes

Structural basis of SARS-CoV-2 polymerase inhibition by Favipiravir

Phylogenomic tracing of asymptomatic transmission in a COVID-19 outbreak

Bridging the knowledge gap on the evolution of the Asian monsoon during 26-16 Ma

Comparative analyses of aging-related genes in long-lived mammals provide insights into natural longevity

Assessing the extent of community spread caused by mink-derived SARS-CoV-2 variants

Geochemical provenancing and direct dating of the Harbin archaic human cranium

A recombinant receptor-binding domain in trimeric form generates protective immunity against SARS-CoV-2 infection in nonhuman primates

Programmed surface on poly(aryl-ether-ether-ketone) initiating immune mediation and fulfilling bone regeneration sequentially

Determining structures in a native environment using single-particle cryo-electron microscopy images

Behavioral innovation promotes alien bird invasions

Urban-rural disparity of the short-term association of PM2.5 with mortality and its attributable burden

Antibody neutralization to SARS-CoV-2 and variants after one year in Wuhan, China

Genomic basis of evolutionary adaptation in a warm-blooded fish

DCLK1 autoinhibition and activation in tumorigenesis

Mechanism of progressive broad deformation from oceanic transform valley to off-transform faulting and rifting

A highly immunogenic live-attenuated vaccine candidate prevents SARS-CoV-2 infection and transmission in hamsters

Specialised digestive adaptations within the hindgut of a colobine monkey

Long-term effects of PM_2.5 components on incident dementia in the Northeastern United States

Mapping the emergence of visual consciousness in the human brain via brain-wide intracranial electrophysiology

Revolution of vitamin E production by starting from microbial fermented farnesene to isophytol

Molecular signatures of parallel adaptive divergence causing reproductive isolation and speciation across two genera

 Section 7

Reviews

Mechanisms of plant responses and adaptation to soil salinity

RNA m⁶A modification in cancers: molecular mechanisms and potential clinical applications

Genomic variation, origin tracing and vaccine development of SARS-CoV-2: A systematic review

Applications and potentials of nanopore sequencing in the (epi)genome and (epi)transcriptome era

Delineating COVID-19 immunological features using single-cell RNA sequencing

Co-existence and co-infection of influenza A viruses and coronaviruses: public health challenges

Single cell technologies: From research to application

 Section 8

Commentaries

New virus, new challenge

Living with salt

Mass testing - an underexplored strategy for COVID-19 control

Key milestones in HCV discovery and therapeutics

Genetic correlations between COVID-19 and a variety of traits and diseases

On the ultimate finishing line of the Human Genome Project

Late Middle Pleistocene Harbin cranium represents a new Homo species

What triggered the Asian elephant’s northward migration across southwestern Yunnan?

Climate change, environmental factors, and COVID-19: Current evidence and urgent actions 

Delta.AR: An augmented reality-based visualization platform for 3D genome

Mass spectrometry imaging-based multi-modal technique: Next-generation of biochemical analysis strategy

2019nCoVR—A comprehensive genomic resource for SARS-CoV-2 variant surveillance

Mechanism of action of favipiravir against SARS-CoV-2: Mutagenesis or chain termination?

Mapping the human brain: What is the next frontier?

From animal to human: Interspecies analysis provides a novel way of ascertaining and fighting COVID-19

原文链接：https://www.cell.com/the-innovation/fulltext/S2666-6758(20)30021-7

DOI: https://doi.org/10.1016/j.xinn.2020.100021

Rapid and accurate identification of SARS-CoV-2 variants containing E484 mutation

Four-month intrinsic viral cycle in COVID-19

American fall webworm in China: A new case of global biological invasions

The mysterious origins of the Omicron variant of SARS-CoV-2

Is the Omicron variant of SARS-CoV-2 coming to an end?

A four-month cycle in COVID-19 cases in Switzerland

Can the “10-year fishing ban” rescue biodiversity of the Yangtze River?

Global impacts of COVID-19 on sustainable ocean development

Why is the SARS-CoV-2 Omicron variant milder?

Another surprise in receptor binding of C. difficile toxins

Opening up the black box of human cell plasticity

Unlocking the secrets to human NTCP structure

MPoxVR – A comprehensive genomic resource for monkeypox virus variants surveillance

From “organs-on-a-chip” to “patient-on-a-chip”

Cancer susceptibility genes: Update and systematic perspectives

Inhalable antibodies for the treatment of COVID-19

Tibetan antelope migration during mass calving as parasite avoidance strategy

Neural circuits underlying motor and non-motor defects of Parkinson’s disease

原文链接：https://www.cell.com/the-innovation/fulltext/S2666-6758(22)00104-7

DOI: https://doi.org/10.1016/j.xinn.2022.100308

Herbgenomics: Decipher molecular genetics of medicinal plants

Palladium membrane electro-hydrogenation

 Section 9

Out-of-the-Box

Who is the missing “matchmaker” between proteins and nucleic acids?

期刊简介

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The Innovation是一本由青年科学家与Cell Press于2020年共同创办的综合性英文学术期刊：向科学界展示鼓舞人心的跨学科发现，鼓励研究人员专注于科学的本质和自由探索的初心。作者来自全球50个国家；已被116个国家作者引用；每期1/4-1/3通讯作者来自海外。目前有195位编委会成员，来自21个国家；50%编委来自海外；包含1位诺贝尔奖获得者，33位各国院士；领域覆盖全部自然科学。The Innovation已被DOAJ，ADS，Scopus，PubMed，ESCI，INSPEC，EI等数据库收录。秉承“好文章，多宣传”理念，The Innovation在海内外各平台推广作者文章。

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See the unseen & change the unchanged

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